Skip to main content
COVID-19 research at Rockefeller

News

 

Vaccines charge up natural immunity against SARS-CoV-2

May 28, 2021
Vaccination enhances antibodies in people who have had COVID, likely giving them protection even from the new variants.
Read more

 

 

Teresa Rozza of Rockefeller’s Clinical Genomics Lab runs COVID saliva tests for the whole university community. (Matthew Septimus)

Study of “breakthrough” cases suggests COVID testing may be here to stay

April 21, 2021
Two new cases helped scientists confirm what many have come to suspect: that people can get infected by SARS-CoV-2 variants even after successful vaccination. The findings suggest continued testing may be needed to prevent future outbreaks in a post-vaccine world.
Read more

 

A volunteer who has recovered from COVID-19 donates blood.

Rockefeller grants commercial license for the development of monoclonal antibodies for treatment of COVID-19

February 3, 2021
The treatment, a combination of two antibodies, has been shown highly capable of neutralizing SARS-CoV-2 in preclinical studies. Researchers hope it will give countries around the world, including developing countries, a way to control the rampant disease.
Read more

 

COVID-19 vaccines may need regular updates for emerging variants

January 29, 2021
Lab experiments suggest that the new strains reported in Britain, South Africa, and Brazil may blunt the potency of the Pfizer and Moderna COVID-19 vaccines. This could mean that the vaccines will need updates as the virus mutates.
Read more

 

Synthetic “micro lungs” could take COVID-19 research to the next level

January 20, 2021
Scientists have developed stem-cell technology to mass-produce tissue cultures resembling our breathing organs. These tissues offer a powerful model in which to study how SARS-CoV-2 wreaks havoc in the lungs and to screen for new drugs.
Read more

 

The immune system mounts a lasting defense after recovery from COVID-19

January 18, 2021
The study participants continued to improve their antibodies months after initial infection, potentially due to exposure to the remnants of the virus hidden in the gut.
Read more

 

The blood may hold clues to some of COVID-19’s most mysterious symptoms

January 15, 2021
COVID-19 causes a host of diverse complications, from lung inflammation to blood clots, heart failure, and brain fog. A team of scientists believes these attributes may have a single culprit—and that findings from research on Alzheimer’s disease might give them a leg up in finding it.
Read more

 

Rockefeller begins testing of new COVID-19 antibody drug in people

January 14, 2021
Patients in the clinical trial will receive two highly potent antibodies against SARS-CoV-2 discovered at the university. Designed to prevent people with early COVID-19 from developing severe disease, the treatment is urgently needed as hospitals continue to be inundated by repeated surges of infection, and mass vaccinations are still months away.
Read more

 

As COVID-19 vaccines emerge, the search for antiviral drugs continues

December 18, 2020
Scientists are digging through drug libraries of 430,000 compounds, in pursuit of an antiviral drug that can stop the novel coronavirus in its tracks.
Read more

 

 

Royalty Pharma and Pablo and Almudena Legorreta Support Development of Antibody-Based COVID-19 Therapy at The Rockefeller University

December 17, 2020
Royalty Pharma and The Rockefeller University announced generous gifts totaling $5,760,000 from Royalty Pharma and Pablo and Almudena Legorreta.
Read more

 

 

MEM41B proteins

Scientists map the network of SARS-CoV-2’s helpers inside human cells

December 16, 2020
The virus must hijack more than a hundred human proteins to replicate inside a cell. One of them stands out because it is an absolute requirement for infection by four different coronaviruses as well as by viruses that cause Zika, yellow fever, and other diseases.
Read more

 

photo of bat

What bats can teach us about COVID-19

December 9, 2020
Unlike most humans, bats are naturally resistant to coronavirus infection. Researchers are now searching their genomes for clues that might explain why SARS-CoV-2 can cause devastating disease in our own species.
Read more

 

covid illustration

Science fights back

November 6, 2020
Researchers have launched a tremendous race to understand the new virus and attack it from every angle. How they work and collaborate might never again be the same.
Read more

 

SARS-CoV-2 particles isolated from a COVID-19 patient are docking onto a host cell

A mediocre mutator

October 15, 2020
Scientists developed a method to safely examine the ability of SARS-CoV-2 to escape future drugs or vaccines by mutating. Their initial results are reassuring.
Read more

 

casanova lab photo

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

September 24, 2020
The findings explain why some people are so vulnerable to the infection, and suggest new avenues for treatment.
Read more

 

 

Bulgari Corporation to support Rockefeller's COVID-19 research and women scientists

September 9, 2020
Over the next three years, the fund will augment the university's wide-ranging research initiatives aimed at alleviating the COVID-19 pandemic, and also support the its women scientists in their training and careers.
Read more

 

 

 

Scientists uncover antiviral protein that blocks coronavirus infection

September 2, 2020
New research identifies a protein that blocks infection by SARS-CoV-2, the coronavirus that causes COVID-19, along with several other types. The findings could inform treatment strategies and help us better prepare for future outbreaks.
Read more

 

 

photo of Fabian Schmidt and Yiska Weisblum

Will SARS-CoV-2 escape future drugs by mutating? The answer may be a nuanced “no.”

August 10, 2020
Scientists hope to deploy antibodies in the quest to end COVID-19. A recent study moves them closer to accomplishing a key step: finding out if the virus may acquire resistance to antibody-based drugs or vaccines, and how to potentially prevent this.
Read more

 

photo of SARS-CoV-2's helicase-polymerase coupling

A never-seen-before image of the coronavirus copy machine

August 7, 2020
The high-resolution 3D image can speed COVID-19 drug discovery.
Read more

 

photo of cells

How toothless mock viruses could advance research on COVID-19

July 31, 2020
Scientists have engineered four viruses resembling SARS-CoV-2 to enable faster and safer research on vaccines and treatments.
Read more

 

photo of hepatitis c helicase

Amid the rush for COVID-19 drugs, a case for the helicase

July 28, 2020
The enzyme is essential for the virus to replicate itself inside our cells. Scientists already have ideas for how to block it.
Read more

 

photo of llama

How antibodies from llamas may lead to COVID-19 treatment

June 11, 2020
Llamas make antibodies that are much smaller than their human counterparts, yet still potent. Scientists hope that future drugs based on these molecules could provide new weapons against SARS-CoV-2.
Read more

 

illustration of antibodies

First results from human COVID-19 immunology study reveal universally effective antibodies

May 25, 2020
New findings characterize human antibody response to SARS-Cov-2, with implications for convalescent plasma therapy, vaccine design, and antibody-based drugs.
Read more

 

Kawasaki disease

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

May 15, 2020
The condition resembles a rare childhood illness, Kawasaki disease. Researchers are analyzing blood samples to find genetic clues to what might be causing it.
Read more

 

DNA on a screen

The gene hunt to explain why some young, healthy people die from COVID-19

April 30, 2020
People under 50 without preexisting conditions typically develop mild symptoms of coronavirus infection—but there are exceptions. Researchers are working to identify rare genetic variations that may explain why some in this group have succumbed to the disease.
Read more

 

A volunteer who has recovered from COVID-19 donates blood.

Scientists are using 'elite' antibodies from COVID-19 survivors to develop potent therapies

April 21, 2020
Most people infected with the coronavirus are able to fight it off because their immune system produces effective antibodies. Rockefeller scientists are working to turn such antibodies into a drug.
Read more

 

 

Stavros Niarchos Foundation donates $3 million to Rockefeller COVID-19 research

April 14, 2020
The grant bolsters Rockefeller’s round-the-clock research initiatives related to COVID-19 and the SARS-CoV-2 virus that causes it.
Read more

 

 

 

Citadel accelerates Covid-19 testing and treatment initiatives to enhance community resilience across the nation

April 6, 2020
The partners of Citadel and Citadel Securities announced $5 million of support to advance scientific relief initiatives at four New York City medical institutions, including Rockefeller.
Read more

 

 

BSL 3 Laboratory

Rockefeller scientists launch a broad range of studies into novel coronavirus

April 3, 2020
Over 130 scientists in 18 labs are conducting research to advance the development of new, urgently needed approaches for the prevention and treatment of COVID-19.
Read more

 

 Vaccines charge up natural immunity against SARS-CoV-2May 28, 2021Vaccination enhances antibodies in people who have had COVID, likely giving them protection even from the new variants.R